高级搜索
5406 例不同类型食管肿瘤临床病理特征对比分析[J]. 肿瘤防治研究, 2007, 34(12): 955-957. DOI: 10.3971/j.issn.1000-8578.49
引用本文: 5406 例不同类型食管肿瘤临床病理特征对比分析[J]. 肿瘤防治研究, 2007, 34(12): 955-957. DOI: 10.3971/j.issn.1000-8578.49
Analysis of Clinicopathological Characteristics for Different Histological Type of Esophageal Neoplasm[J]. Cancer Research on Prevention and Treatment, 2007, 34(12): 955-957. DOI: 10.3971/j.issn.1000-8578.49
Citation: Analysis of Clinicopathological Characteristics for Different Histological Type of Esophageal Neoplasm[J]. Cancer Research on Prevention and Treatment, 2007, 34(12): 955-957. DOI: 10.3971/j.issn.1000-8578.49

5406 例不同类型食管肿瘤临床病理特征对比分析

Analysis of Clinicopathological Characteristics for Different Histological Type of Esophageal Neoplasm

  • 摘要: 目的 探讨小细胞癌、癌肉瘤等少见食管肿瘤以及小年龄组食管肿瘤的临床病理特征。方法 回顾性分析5406例食管肿瘤术后的病理诊断结果,观察各种肿瘤的早诊率、淋巴结转移率及年龄分布情况,对比分析所见各种食管肿瘤的特点。结果 5406例中29例双原癌(同时合并贲门腺癌);5377例均为单发食管肿瘤,其中鳞癌95.5%,腺鳞癌1.8%,腺癌0.5%,其他类型4%。全部病例中早诊率为9.1%,淋巴结转移率为39.6%。各型早诊率和淋巴结转移率之间差异无显著性(χ2=7.384,12.677;P=0.597,0.178)。小细胞癌与鳞癌的淋巴结转移率之间差异有显著性(χ2=4.704,P=0.030)。小年龄组(≤40岁)与其他年龄组比较,两组间早诊率及淋巴结转移率差异均无显著性(x^2=0.186,0.558;P=0.666,0.455)。结论 食管胸中段是各型肿瘤的好发部位。食管肿瘤以鳞癌最多,腺鳞癌次之,其次为小细胞癌、腺癌及癌肉瘤等。各型肿瘤的早诊率及淋巴结转移率均相似,仅小细胞癌淋巴结转移率明显高于鳞癌。各年龄段食管肿瘤早诊率及淋巴结转移率无统计学差异。提高食管肿瘤的早诊率是亟待解决的问题。

     

    Abstract: Objective  To explore the clinicopathological characteristics for different histological type of esophageal neoplasms ( EN) . Methods  To observe the rate of each typical ENs's early stages ( ES), the rate of lymph node metastasis (LNM), and feature of it s distribution, 5 406 patients with ENs were ret rospectively reviewed. Results  Twenty-nine patients were concurrent cancer, other patients suffered from single esophagueal disease. The rate of squamous carcinoma, adeno-squamous carcinoma and adenocarcinoma was 95. 5 %, 1. 8 % and 0. 5 %, respectively, the others was 4 %. The rates of ES and LNM were 9. 1 % and 39. 6 %. The difference of the rate of ES and LNM between each type was not significant (χ2 =7. 384, 12. 677 ; P = 0. 597, 0. 178) . But the rate of LNM was significant different between small cell carcinoma and squamous carcinoma ( P < 0. 05) . Conclusion  Most of EN were found in middle segment, squamous carcinoma was absolute major EN, the following was adeno-squamous carcinoma, small cell carcinoma, adeno-carcinoma and carcinosarcoma. The rate of LNM of small cell carcinoma was significant different from squamous carcinoma's. The rate of ENs and LNM in each age's had no significant difference.

     

/

返回文章
返回