Abstract: Objective 　To investigate the life quality of advanced Lewis lung cancer with Yiqi Yangyin Qin2 gre Huatan t raditional Chinese medicine. Methods 　We established the thoracic cavity implant model of the C57BL/ 6 mice bearing Lewis lung carcinoma and divided into three groups randomly. Each group contained 10 mice. The MPA Group (0. 2 ml) (16 mg/ kg·d) and YiQi Yangyin Qingre Huatan t raditional Chinese medicine group (0. 2 ml) and NS group (0. 2 ml) . The groups were administ rated were given to give Chinese medicine, NS 0. 2 ml by int ragast ric administ ration af ter cancer cachexia for eight days. Ob2 serve the quality of life of mice and The expression of TNF2α、IL26 in the lung cancer tissue by immuno2 histochemist ry. Results 　(1) Consumption of feed and weight : there were significantly differences among NS group and the MPA Group and TCM group. (2) IHC: TNF2α and IL26 expression in TCM group and MPA Group were significantly lower than cont rol group. Conclusion 　The t raditional Chinese medi2 cine is helpful to improve the occurrence and growth of lung cancer.