鼻咽癌放疗完全缓解后腔内照射补量

Intracavitary Brachytherapy Boost for Complete Responders to Traditional Curative Radiotherapy

摘要: 目的研究鼻咽癌放疗完全缓解后腔内照射补量的剂量效应关系。方法1992年2月~1999年12月92例根治性放疗65~70Gy后完全缓解T1、T2患者行近距离腔内补量照射,1975年11月~2000年12月收治的根治性放疗后完全缓解未进一步治疗的T1、T2患者206例为对照。结果T1、T2根治性放疗后完全缓解未加量组、根治性放疗后完全缓解腔内补量组5年生存率分别为78.28%、85.14%。根治性放疗后完全缓解腔内补量<80Gy者与≥80Gy者5年生存率分别为78.2%、85.9%。结论早期鼻咽癌传统根治性放疗后相对抗拒肿瘤腔内补量提高了局部控制,可进一步改善生存。

Abstract: Objective To evaluate the result of intracavitary brachytherapy boost for nasopharyngeal carcinoma. Methods For patients with carcinoma of nasopharynx in T1T2 stage, from February 1992 to December 2000, 92 patients delivered intracavitary brachytherapy boost for complete responders to traditionale curative radiotherapy; To compare the efficacy of intracavitary brachytherapy boost for complete responders, from November 1975 to December 2000, 206 patients with complete responder to curative radiotherapy were ...