急性白血病糖代谢功能的临床研究

Clinical study on blood glucose of patients with acute leukemia

摘要: 目的　探讨急性白血病患者血糖代谢功能变化及其临床意义, 并分析糖代谢异常发生的机理。方法　分别于急性白血病患者化疗前后抽取空腹血, 用组织化学及放射免疫方法检测血糖、肝脏和胰腺功能, 分析血糖异常对急性白血病缓解率的影响。结果　 36例急性白血病患者, 17例血糖代谢异常, 19例肝功能减低, 9例胰岛素、C肽含量减低, 12例胰高血糖素升高。急性白血病患者血糖正常者缓解率 (78.9% )明显高于血糖异常者 (41.1% )。结论　急性白血病患者易发生血糖代谢异常, 血糖代谢异常时急性白血病缓解率低, 血糖代谢异常可能与肝功能减低和胰岛α、β细胞功能障碍有关

Abstract: Objective To evaluate the clinical significance of abnormal blood glucose of patients with acute leukemia and try to find out it s mechanism . Methods The function of liver and pancreas were examined before and after chemthrapy of acute leukemia by chemistry and radioimmunolgy . Results In 36 cases with acute leukemia, it was found that abnormal blood glucose in 17 cases, decreas of founction of cells of liver in 19 case, decrease of isolin and C peptide in 12 cases. In the same time,it was found that r...