MOC-31在胸膜间皮瘤与肺癌鉴别诊断中的应用
Value of MOC-31 in differentiating epithelial pleural mesothelioma from non small cell lung carcinoma
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摘要: 目的 研究MOC 31在胸膜间皮瘤与肺癌鉴别诊断中的应用价值。方法 采用免疫组化 (S P)方法对 81例非小细胞肺癌 (non smallcelllungcarcinomaNSCLC) 13例胸水脱落的肺癌细胞, 9例上皮型胸膜间皮瘤和 2 2例胸水脱落的间皮细胞进行MOC 31检测。结果 MOC 31在NSCLC、胸水脱落的癌细胞、胸膜间皮瘤及胸水脱落的间皮细胞的阳性率分别为 98.8%、84 .6 %、11.1%及 9.1%。MOC 31在NSCLC及胸水中肺癌细胞的阳性率, 明显高于间皮瘤及胸中间皮细胞的阳性率 (P <0 .0 0 1), 而间皮瘤与胸水间皮细胞的阳性率无统计学差异 (P >0 .0 5 )。结论 MOC 31在胸膜间皮瘤与NSCLC的鉴别诊断中有重要的参考价值。对判定胸水的性质也有重要意义。Abstract: Objective To study the value of MOC-31 in differentiating diagnostically epithelial pleural mesothelioma from NSCLC. Methods Immunohistochemical method (S-P)was used to detect MOC-31 in 81 caes of NSCLC,13 cases of lung cancer cells in serous fluids,9 cases of epithelial pleural mesothelioma and 22 cases of mesothlial cells in serous fluids. Results The positive rate of MOC-31 in NSCLC lung cancer cells of serous fluids,epithelial pleural mesothelioma and mesothelial cells of serous fluids were 98.8%,84...
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