芬太尼与曲马多联合自控静脉镇痛用于肺癌根治术后的观察

Clinical observation of patient-controled infusion(PCIA) with fentanyl and tramadol on inpatients undergoing radical operation of lung cancer

摘要: 目的　本文旨在观察芬太尼、曲马多联合应用于肺癌根治术后的镇痛效果。方法　选择 2 4 0例ASAⅠ～Ⅱ级肺癌根治术的患者, 随机分为 3组, 每组 80例 :A组芬太尼 0 .8mg ;B组芬太尼 0 .4mg +曲马多 4 0 0mg ;C组曲马多 80 0mg。结果　 (1)A、B组镇痛效果、患者满意程度明显优于C组且有极显著差异 (P<0 .0 1)。 (2 )A组呼吸抑制为 2 .5 %而B、C组均为 0。C组恶心呕吐、头晕头昏与A、B组存在显著差异 (P<0 .0 5 )。 (3)B组芬太尼、曲马多用量比A、C组极显著减少 (P <0 .0 1)。 (4)PCA泵按压的有效次数无效次数A≈B >C组。结论　芬太尼与曲马多联合自控静脉镇痛是用于肺癌根治术后较为安全、有效的方法。

Abstract: Objective To observe the analgesia effect on radical operation of lung cancer with fentanyl and tramadol for postoperative analgesia. Methods 240 patients (ASA status I or Ⅱ) undergoing radical operation were randomly divided into three groups : group A ( n = 80) fentanyl 0.8mg; group B ( n = 80), fentanyl 0.4mg with tramadol 400mg ; group C ( n = 80) : tramadol 800mg . Results ① The analgesia effect and the overall satisfaction degree in group ...