16例骶尾部脊索瘤放疗随访5年疗效观察

Effect of radiotherapy on chordoma in sacrum caudal region 5-year follow-up of 16 cases

摘要: 目的　探讨放疗在骶尾部脊索瘤临床治疗中的作用。方法　采用常规分段治疗。第 1段DT4 0Gy/ 2 0次 / 4周, 休 2周 ;第 2段DT30GY/ 15次 / 3周。随访 5年。结果　 16例骶尾部脊索瘤术后放疗或单纯性姑息放疗, 不仅可使术后复发明显减少 (本组术后放疗复发率为 15 .38% ), 而且使术后遗留症状得到改善, 甚至消失。大剂量分段放疗的患者均未发生放射性损伤。结论　手术后放疗或单纯姑息性放疗能有效控制瘤体生长, 延长生存期。文献提出脊索瘤对放射线不敏感的说法是否准确值得进一步探讨

Abstract: Objective To discuss and explore the clinical effect of radiotherapy for chordoma in sacrum caudal region. Methods Routine period radiotherapy:Primary stage : DT40GY/20 times/4 weeks,rest2 weeks ;Second stage :DT30GY/ 15 times / 3 weeks,5years follow-up. Results According to the 13 cases of Post-operative radiotherapy for chordoma in sacrum caudal region and 3 cases of singly palliative radiotherapy,we find it can not only obviously decrease the post-operation recurrence,but also improve the post-ope...