Abstract: Objective To avoid or reduce anastomotic stenosis leakage and reflux esophagitis of post-esophagogastrotomy for patients with carcinoma of esophagus and cardia.We design the elliptical esophagogastromosis.Metho ds Forty hybrid dogs were separated into two groups randomly (elliptical a nastomosis in 20 and conventienal methods in 20).Two hundred and two patients t r eated with elliptical anastomosis in which 60 cases examined.One hundred and six patients underwent conventional methods and 45 patients tested. Results There were no anastomotic stenosis in group A dogs and four dogs appear an as tomotic stenosis (P<0.05).The leading capability of anastomosis in group A was better than group B on pathological examination.All dogs were no reflux in g roup A and over 1/2 dogs were reflux in group B (P<0.05).The average diamet er of anastomosis in elliptical anastomosi s was 2.02±0.38cm and conventional methods were 1.35±0.82cm (P<0.01) i n all patients.The mucus congestion edema and pH in esophagus were significantly different (P<0.05) within two groups. Conclusion Elliptical ana stomosis was superior to conventional methods.It was worth poputarizing after es ophagogastrectomy for carcinoma of the esophagus and cardia.