直肠癌切除后结肠袋状吻合的生理机能评价
Evaluation of Physiologic Function of Colonic Pouch Anastomoses after Rectal Cancer Excision
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摘要: 目的 探讨直肠癌前切除术后结肠袋状吻合的生理学特征。方法 将 4 6例中段直肠癌切除患者随机分为A、B两组, A组行直接吻合术, B组行结肠袋状吻合术, 对两组病例的新直肠的生理机能进行评估, 其中包括实验室研究。结果 两组病例术后其括约肌压力相似, B组病例术后直肠的顺应性得以恢复, 其顺应性为 0 .2 96 (0 .2 2 4～ 0 .347)L/kPa, 而A组病例术后顺应性下降, 顺应性为 0 .194 (0 .112～0 .2 35 )L/kPa, 两组比较顺应性差异非常显著 (P <0 .0 0 1)。多元回归分析提示新直肠的顺应性与有利的临床机能有关, 而肛管运动与不利的临床机能有关。结论 结肠袋状肛管吻合能恢复新直肠的顺应性, 并对直肠癌低位切除后维持其较好的生理机能非常重要Abstract: Objective To study physiology value of colonic pouch anastomoses after rectal carcinoma excision. Methods 46 patients with total mesorectal excision for carcinoma were randomized into two groups,i.e., straight(Group A,n=23)and colonic pouch anastomosis(Group B,n=23).Neorectal physiologic function of patients in both groups was evaluated including laboratory studies. Results The results showed that sphincter pressures in both groups were similar. Preoperative compliance of the rectum was restored after sur...
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