Abstract: Objective To observed the effects of canmai liquor in combination with chemotherapy on the increase of chemotherapeutic results,reduction of chemotherapy-induced toxicities and on human functions. Methods 108 cases with late-stage cancer were treated with canmai liquor combining with chemotherapy or only chemotherapy.The results of treatment,immune functions and chemotherapy-induced toxicities were observe. Results The remission rate of the trial group was 56.45% and significantly higher than that(39.13%) of the control group(P＜0.05).The Chemotherapy induced morbidity of oral mucosal ulcer and venulitis of the trial group reduced in comparison to the control group(P＜0.05 or 0.01).White blood cell count reduced significantly in control group(P＜0.01),but not in trial group.Changes of cellular immune function:In the trial group,the natural Killer Cells,CD4 and CD4/CD8 ration increased,CD8 reduced(P＜0.05 or 0.01).The humoral immunity of two hroups had no obvious change(P＞0.05). Conclusion Canmai liquor in combination with chemotherapy could raise the remission rate of treatment,reduce the chemotherapy-induced toxicities and improve the cellular immune function.