血清及肌瘤匀浆液雌二醇、孕酮测定在子宫肌瘤发病中意义的探讨
Significance of E2,PRO Level in Serum and Tissue Extraction of Patients with Utcrus Myoma
-
摘要: 目的 对雌、孕激素在子宫肌瘤发病中的意义进行探讨。方法 2 4例子宫肌瘤患者, 年龄 34～ 51岁, 分别于手术前后测定血清中雌二醇 (E2 )、孕酮 (PRO)水平, 计算E2 PRO比值并与 2 0例同年龄段健康体检女性进行对照。另术中取小块肌瘤及正常肌层组织制备成匀浆液测定E2、PRO。测定方法为放射免疫分析法。结果 病例组血清E2水平及E2 PRO比值明显低于对照组, PRO变化无意义 ;匀浆液测定肌瘤组织E2含量及E2 PRO比值高于正常肌层组织, 有显著性差异。结论 子宫肌瘤患者血清E2 PRO比值异常是子宫肌瘤发病的重要因素, 肌瘤局部组织内E2含量明显升高及E2 PRO比例失调可能是子宫肌瘤发病的直接原因。Abstract: Objective assess significance of Estradiol(E2)、Progesterone(PRO) level in serum and tissue extraction of patients with uterus myoma. Methods 24 paticnts with utcrus myoma were studied(age of 34～51 years old).Their serum E2、PRO content was determined by RIA pre-and post-operation.E2/PRO ratio was calculated.So did control group of 20 cases.A piece of myoma and normal muscle tissue was taken just the time for operation and this samples were extracted;the E2,PRO level of extraction was detected by RIA. Results T...
下载:
