雌激素受体水平测定与青年乳腺癌的预后

doi:10.3971/j.issn.1000-8578.2032

雌激素受体水平测定与青年乳腺癌的预后

ER Level at the Prognosis of Young Breast Cancer

摘要

摘要: 目的　探讨研究雌激素受体(ER)水平对青年乳腺癌预后的影响及术后治疗的指导作用。方法　根据ER水平，将收治的78例35岁以下青年女性原发乳腺癌分成ER(+)和ER(-)两组。按Kaplan-Meier法计算。并按时序检验比较两组生存曲线的趋势。结果　ER(+)组48例，中位随访时间95个月(13～120月)，13例出现复发转移，复发转移率为27.1%(13/48)。ER(-)组30例，中位随访时间为65个月(1～120月)，16例出现复发转移，复发转移率为53.3%(16/30)。ER(+)组术后复发转移率明显低于ER(-)组(P<0.05)。结论　ER是青年女性乳腺癌术后的一个重要预后参考因素。ER(+)组10年无病生存率明显高于ER(-)组。

Abstract: Objective To study ER (Estrogen Receptor) level for the influence of prognosis of young female breast cancer patients and evaluation and guidance post operation therapy. Methods Depending on their ER Level.They are divided into two groups from 78 cases of the young female breast cancer patients.Using Kaplan-Meier method to evaluate diseases free survival (DFS) rate frame date of operation. Results There were 30 cases patients ER(一)，and 48 cases patients ER(+) of two group The medium follow up time of the ER(+) and ER(-) group was 95.0 and 65.3 months,respectively.The instance of recurrence and metastasis was 27.1%(13/48) in ER(+) group and 53.30%(16/30) ER(-) group (P<0.05). Conclusion ER Level is a most important reference factor in prognosis of Young breast patients.

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