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王银, 李波, 宋建民. INTRABEAM术中放疗在软组织肿瘤保肢治疗中的应用(附4例报告)[J]. 肿瘤防治研究, 2022, 49(12): 1283-1285. DOI: 10.3971/j.issn.1000-8578.2022.22.0462
引用本文: 王银, 李波, 宋建民. INTRABEAM术中放疗在软组织肿瘤保肢治疗中的应用(附4例报告)[J]. 肿瘤防治研究, 2022, 49(12): 1283-1285. DOI: 10.3971/j.issn.1000-8578.2022.22.0462
WANG Yin, LI Bo, SONG Jianmin. INTRABEAM Intraoperative Radiation Therapy Combined with Limb Sparing Surgery in Soft Tissue Sarcoma (A Report of Four Cases)[J]. Cancer Research on Prevention and Treatment, 2022, 49(12): 1283-1285. DOI: 10.3971/j.issn.1000-8578.2022.22.0462
Citation: WANG Yin, LI Bo, SONG Jianmin. INTRABEAM Intraoperative Radiation Therapy Combined with Limb Sparing Surgery in Soft Tissue Sarcoma (A Report of Four Cases)[J]. Cancer Research on Prevention and Treatment, 2022, 49(12): 1283-1285. DOI: 10.3971/j.issn.1000-8578.2022.22.0462

INTRABEAM术中放疗在软组织肿瘤保肢治疗中的应用(附4例报告)

INTRABEAM Intraoperative Radiation Therapy Combined with Limb Sparing Surgery in Soft Tissue Sarcoma (A Report of Four Cases)

  • 摘要:
    目的 探讨外科手术联合INTRABEAM术中放疗在软组织肉瘤保肢治疗中的临床疗效。
    方法 回顾性分析2020年7月到2021年10月收治的4例肢体软组织肉瘤患者,接受保肢手术联合INTRABEAM术中放疗治疗,手术过程顺利,无麻醉及手术意外发生。
    结果 4例患者均接受随访,时间从6~22月不等。1例术后2月局部复发,患者拒绝截肢,行化疗及靶向治疗;1例术后10月发生肺转移,行手术切除;1例复发患者肢体功能差,余3例患者肢体功能正常。
    结论 外科手术联合INTRABEAM术中放疗可以在保留肢体功能的同时提高局部控制率,提高了患者的生存质量。

     

    Abstract:
    Objective To explore the clinical efficacy of surgical operation combined with INTRABEAM intraoperative radiotherapy in the limb-sparing treatment of soft tissue sarcoma.
    Methods A retrospective study was performed on four patients with limb soft tissue sarcoma admitted from July 2020 to October 2021 who received limb sparing surgery combined with INTRABEAM intraoperative radiotherapy. The operation went smoothly without anesthesia or accident.
    Results All the four patients received follow-up, ranging from 6 to 22 months. One patient had local recurrence two months after the surgery, and the patient refused amputation and received chemotherapy and targeted therapy. One patient had pulmonary metastasis ten months after the surgery and underwent surgical resection. One recurrent patient had poor limb function, and the other three patients had normal limb function.
    Conclusion Surgical operation combined with INTRABEAM intraoperative radiotherapy can preserve limb function while improving local control and quality of life.

     

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