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金龙, 徐大蒙, 周园园, 于娇. 18F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的应用[J]. 肿瘤防治研究, 2022, 49(5): 453-458. DOI: 10.3971/j.issn.1000-8578.2022.21.0912
引用本文: 金龙, 徐大蒙, 周园园, 于娇. 18F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的应用[J]. 肿瘤防治研究, 2022, 49(5): 453-458. DOI: 10.3971/j.issn.1000-8578.2022.21.0912
JIN Long, XU Dameng, ZHOU Yuanyuan, YU Jiao. Application of 18F-FDG PET-CT Simulation Localization in Radiotherapy of Recurrent Abdominal and Pelvic Tumors[J]. Cancer Research on Prevention and Treatment, 2022, 49(5): 453-458. DOI: 10.3971/j.issn.1000-8578.2022.21.0912
Citation: JIN Long, XU Dameng, ZHOU Yuanyuan, YU Jiao. Application of 18F-FDG PET-CT Simulation Localization in Radiotherapy of Recurrent Abdominal and Pelvic Tumors[J]. Cancer Research on Prevention and Treatment, 2022, 49(5): 453-458. DOI: 10.3971/j.issn.1000-8578.2022.21.0912

18F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的应用

Application of 18F-FDG PET-CT Simulation Localization in Radiotherapy of Recurrent Abdominal and Pelvic Tumors

  • 摘要:
    目的 探讨18F-FDG PET-CT模拟定位在复发腹盆腔肿瘤放疗中的临床价值。
    方法 采用18F-FDG PET-CT对38例治疗后复发的腹盆腔肿瘤患者进行模拟定位, 分别根据CT影像及18F-FDG PET-CT拟定全身治疗方案及放疗靶区勾画, 对比二者差异。
    结果 在38例患者中, 21.1%(8/38)发现了盆腹腔外远处转移, 改变了治疗方案。34例(89.5%)放射治疗靶区发生了改变。GTVPET-CT的均值为118.14 cm3, GTVCT的均值为148.53 cm3(P=0.044)。
    结论 18F-FDG PET-CT模拟定位对于复发盆腹腔肿瘤患者, 完善了肿瘤再分期, 改变了部分患者治疗方案, 更加精确放射治疗靶区。

     

    Abstract:
    Objective To investigate the clinical application value of 18F-FDG PET-CT simulation localization in radiotherapy of recurrent abdominal and pelvic tumors.
    Methods 18F-FDG PET-CT was used to simulate positioning 38 patients with abdominal and pelvic tumors who relapsed after treatment.Based on both CT images and 18F-FDG PRT-CT, we drew up a systemic treatment plan and outlined the radiotherapy target area, and then compared the differences between the two methods.
    Results In 38 patients, 21.1%(3/8) of patients were found to have distal metastases outside the pelvic and abdominal cavity, and changed the systemic treatment plan.The radiotherapy target was altered in 34(89.5%) patients.The mean value of GTVPET-CT was 118.14cm3and the mean value of GTVCT was 148.53cm3(P=0.044).
    Conclusion For patients with recurrent abdominal and pelvic tumors, 18F-FDG PET-CT simulation localization treatment improves tumor re-staging, changes the integrated therapy for some patients, and makes the target area of radiotherapy more accurate.

     

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