Abstract:
Objective To analyze whether schistosomiasis japonica has a certain correlation with the occurrence of intestinal cancer and investigate the characteristics of intestinal cancer with schistosomiasis.
Methods We retrospectively analyzed the clinical data, pathological and laboratory examination results of 187 colorectal cancer patients with schistosomiasis treated in Yijishan Hospital of Wannan Medical College from Jan. 2013 to Dec. 2017. In addition, 2597 colorectal cancer patients without schistosomiasis were included as control group in the same period.
Results Among these patients with schistosomiasis, males were significantly more than females (P=0.002); the average age was significantly higher than the control group (64.79±10.91) vs. (61.63±11.86) years old, P=0.001), especially after 60 years old (P=0.007). The number of red blood cells in both groups was lower than the normal value (P=0.01). The positive number of fecal occult blood in colorectal cancer patients with schistosomiasis was significantly higher than that in the control group (119 (63.64%) vs. 1344 (51.75%), P=0.002). The levels of CEA and CA199 in both groups were significantly higher than normal value.
Conclusion Colorectal cancer with schistosomiasis has clinical characteristics. For the residents in schistosomiasis endemic areas, especially middle-aged and elderly men, it is suggested that serum tumor markers and gastrointestinal endoscopic examination should be performed regularly to detect the possibility of schistosomiasis combined with digestive tract tumors as early as possible.
下载:
