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崔云鹏, 施学东. 脊柱转移瘤治疗进展[J]. 肿瘤防治研究, 2018, 45(5): 337-342. DOI: 10.3971/j.issn.1000-8578.2018.17.1262
引用本文: 崔云鹏, 施学东. 脊柱转移瘤治疗进展[J]. 肿瘤防治研究, 2018, 45(5): 337-342. DOI: 10.3971/j.issn.1000-8578.2018.17.1262
CUI Yunpeng, SHI Xuedong. Progress of Treatment on Metastatic Spinal Tumors[J]. Cancer Research on Prevention and Treatment, 2018, 45(5): 337-342. DOI: 10.3971/j.issn.1000-8578.2018.17.1262
Citation: CUI Yunpeng, SHI Xuedong. Progress of Treatment on Metastatic Spinal Tumors[J]. Cancer Research on Prevention and Treatment, 2018, 45(5): 337-342. DOI: 10.3971/j.issn.1000-8578.2018.17.1262

脊柱转移瘤治疗进展

Progress of Treatment on Metastatic Spinal Tumors

  • 摘要: 脊柱是骨转移瘤最常见的部位。脊柱转移瘤引起的剧烈疼痛、脊髓压迫以及神经功能损害,严重影响患者生活质量。既往对脊柱转移瘤治疗方式的选择主要建立在Tomita、Tokuhashi等预后评分基础上,包括放疗和手术治疗。随着研究的不断深入,临床医生能够更好的判断患者的生活质量和生存预后;加之一系列新治疗技术的出现,能够安全有效的缓解患者的临床症状,并缩短患者的术后恢复时间,使得脊柱转移瘤患者更易于接受治疗。特别是立体定向体部放射治疗、外科微创技术和靶向治疗的出现,将脊柱转移瘤的治疗带进一个新时期。

     

    Abstract: The spine is the most common site of bone metastases. Massive pain, spinal cord compression and neurological dysfunction are common manifestations of spine metastases, negatively impacting the patients' quality of life. Previously, treatment options for spinal metastases, including radiotherapy and surgical treatment, were based primarily on prognostic scores such as Tomita or Tokuhashi. We now have a better understanding of which factors influence survival and quality of life after surgery, and several new techniques have been developed over the past decade to make surgery for spinal metastases safer and more acceptable to patients by decreasing postoperative pain and length of hospital stay. Especially, stereotactic body radiation therapy, minimally invasive techniques and targeted therapy have revolutionized the management of metastatic spine tumors.

     

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