35例食管腺样囊性癌的临床特征及预后分析

张国亮; 曾辉; 王涛; 朱奇坤; 张丹丹; 王瑞

doi:10.3971/j.issn.1000-8578.2018.17.0627

35例食管腺样囊性癌的临床特征及预后分析

Clinical Characteristics and Prognostic Factors of 35 Patients with Esophagus Adenoid Cystic Carcinoma Patients

摘要

摘要:
目的分析食管腺样囊性癌（esophagus adenoid cystic carcinoma, EACC）的临床特点、诊断、治疗方式及预后。
方法回顾性分析35例EACC患者的病例资料，分析EACC的临床病理特征及预后影响因素。
结果 35例腺样囊性癌多发于食管中段，平均年龄60.6岁，男女比例4:1，病理形态以蕈伞型和息肉型为主。早期EACC神经受侵发生率低，实性型较经典筛状型复发转移率高，患者中位生存期为38月，术后1、3、5年生存率分别为88.1%、46.6%和27.1%。
结论发生于食管的腺样囊性癌是一种罕见的恶性肿瘤，其预后与肿瘤大小、病理分期相关。

Abstract:
Objective To analyze the clinical characteristics, diagnosis, treatment and prognosis of the esophagus adenoid cystic carcinoma(EACC).
Methods We collected the clinical data of 35 patients treated with surgical resection of underlying tumors and pathologically confirmed as EACC. Clinicopathologic characteristics and prognostic factors were analyzed.
Results EACC was commonly observed at middle-esophagus, with an average age of 60.6 years old and male-to-female ratio of 4:1. The major pathological type of EACC was umbrella and polypoid. EACC was less frequently accompanied by nerve invasion, especially at the early stage. The recurrence and metastasis rates were higher in solid tumors than those in cribriform tumors. The median survival time was 38 months, and the average 1-, 3-and 5-year survival rates were 88.1%, 46.6% and 27.1%, respectively.
Conclusion Adenoid cystic carcinoma(ACC) is a very rare malignant tumor in the esophagus. The tumor size and pathological stage are related to the prognosis of EACC.

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