Abstract:
Objective To investigate the morbidity, clinical manifestations, endoscopic and pathological characteristics of colorectal cancer in the Endoscopic Center of The Affiliated Hospital of Zunyi Medical College from 2007 to 2016, and further expound the epidemiological and clinical characteristics of colorectal cancer in local district.
Methods All patients treated with colonoscopy in The Affiliated Hospiatal of Zunyi Medical College in the past 10 years were involved. We analyzed and summarized the morbidity of colorectal cancer and colorectal cancer patients' gender and age, tumor location and pathological type retrospectively.
Results We examined 51732 cases by colonoscopy in the past 10 years, among which 2127(4.11%) cases were colorectal cancer(1267 males and 860 females; 714 cases of colon cancer and 1413 cases of rectal cancer). The peak age of onset was 50-79 years old, especially 60-69 years old. Adenocarcinoma was the mainly pathological classification, especially well-differentiated adenocarcinoma, and they were not significantly different in gender. But the number of female patients with signet-ring cell carcinoma were more than male patients (P < 0.05).
Conclusion In recent years, the incidence of colorectal cancer has been increasing in the north of Guizhou Province. The number of male patients is more than females. The incidence of rectal cancer is about two times as much as colon cancer. The female patients with colorectal cancer must be paid attention to the occurrence of signet ring-cell carcinoma in pathological classification. We must strengthen the survey on colorectal cancer, rectal digital examination and colonoscopy in high-risk people, which can improve early diagnosis and treatment of colorectal cancer.
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