Objective To explore imaging findings of primary hemangiopericytoma of bone.

Methods The clinical, X-ray, CT and MRI findings were analyzed in five cases with primary hemangiopericytoma of bone.

Results In five patients, two cases of multiple lesions showed extensive multiple bone destruction on X-ray plain film. The trabecular bone was thickening like honeycomb and latticed change. Bone cortex was mild expansion and thinning. Three cases of single lesion in long bone were concentric bone destruction, including two cases with soft tissue mass. Three patients underwent CT scan, of which one case in sacrum and ilium lesion presented osteolytic bone destruction with local bone cortex interruption. Two cases of single lesion showed local bone destruction associated with soft tissue mass with uneven density. Two patients underwent MR examination. The tumor showed iso-or low signal intensity on T1WI and mixed iso-or slightly high signal intensity on T2WI. After contrast-enhanced scan, the tumor was heterogeneous obvious enhancement.

Conclusion Most primary hemangiopericytoma of bone occurs in the pelvis and long bone of lower limbs. The tumor mainly showed osteolytic bone destruction with or without soft tissue mass, no periosteal reaction. Although no obvious characteristic can be found on imaging findings, it can help to understand the scope of the lesions, formulate treatment measures and evaluate treatment effect.