宫颈癌调强放疗中靶区退缩研究

IMRT for Cervical Cancer:Study of Target Region Regression

摘要: 目的研究宫颈癌患者放疗前后靶区的退缩情况。方法随机选取20例宫颈癌调强放疗患者，采集放疗前CT与放疗后CT图像，勾画出CTV 及GTV肿瘤轮廓，分析其放疗后的退缩情况。结果20例患者的CTV及GTV肿瘤退缩明显，数据显示CTV平均退缩了17.3%，GTV肿瘤平均退缩了48.2%，并给临近危及器官吸收剂量带来影响。结论放疗期间CTV及GTV肿瘤退缩十分明显，应密切观察其退缩情况。对于个别GTV肿瘤较大的患者，其退缩对临近危机器官的影响不容忽略，必要时应重新制作治疗计划。

Abstract: Objective To investigate tumor regression in patients with intact cervical cancer. Methods We analyzed 20 patients undergoing intensity-modulated radiation therapy,scanning CT image before and after radiotherapy to study tumor regression. Results Data show that CTV average regression is 17.3%,GTVtumor average regression is 48.2%,and there is influence on adjacent organs. Conclusion Obvious regression of CTV and GTV tumor in radiotherapy is observed.Individual patients with large GTV tumor,should be closely observe its regression and impact to adjacent organs,if necessary,should re-create the treatment plan.