Abstract:
Objective To investigate the effect and toxicity of treatment with three dimensional-conformal radiotherapy and low-dose Cisplatin on the elderly patients with non-small cell lung cancer (NSCLC). Methods To retrospectively analyze the effect and toxicity of 36 elderly NSCLC patients with aging greater or equal to 75,all the patients were given 3DCRT with 50~60 Gy and paclitaxe Cisplatin chemotherapy. Results CR was achieved in 7 cases,PR in 19 cases,SD in 6 cases,PD in 4 cases,the overall response rate (CR+PR) was 72.2% and the clinical benefit rate (CR+PR+SD) was 88.9%.The important adverse effects were radiation esophagitis,gastrointestinal toxicity and bonemarrow suppression. Conclusion Three dimensional-conformal radiotherapy combined with low-dose cisplatin for elderly patients with non-small cell lung cancer was safe and effective,the toxicity was tolerable.