Abstract: ObjectiveTo investigate the clinical epidemiological characteristics of gastric carninoma and its trend during the past 33 years in Hexi Corridol,Gansu province. Methods Patients with gastric carcinoma,detected by endoscopy and pathologically diagnosed from January 1977 to December,2009 were selected.The main clinical data,epidemiologyical,endoscopic manifestation and the pathological characteristics were studied. Results The overall diagnosis rate of gratric carcinoma was 5.57% in the past 33 years.The predominant age range from 50 to 69 years old,with the majority being the men,and the gastric carcinoma mainly occurred in the cardia,body and sinus.The adenocarcinoma took large part and the percentage of low adenocarcinoma was high about 38.88%.The hightest rate of detection was Wuwei(6.39%). Conclusion The diagnosis rate of gratric carcinoma in Hexi Corridol during the past 33 years had the significant falling trend.However,the diagnosis rate of early gratric carcinoma was very low,therefore,early prevention and control work for this disease is very important.