联合检测血清CA153和TSGF对胶质瘤的诊断价值

doi:10.3971/j.issn.1000-8578.2009.12.017

联合检测血清CA153和TSGF对胶质瘤的诊断价值

Evaluation of Combined Determination of Serum CA153 and TSGF in Diagnosis of Human Gliomas

摘要

摘要: 目的探讨血清CA153和TSGF联合检测在胶质瘤诊断中的价值。方法采用免疫放射量度分析法和分光光度比色法测定58例胶质瘤患者血清中CA153和TSGF的表达水平。结果胶质瘤患者血清中CA153和TSGF的表达水平明显高于脑非胶质瘤良性肿瘤和健康对照组（P<0.05）,低级别胶质瘤与高级别胶质瘤之间表达水平差异亦有统计学意义（P<0.05）,两者联合检测能提高对脑胶质瘤的诊断率。结论联合检测血清CA153和TSGF对脑胶质瘤的早期诊断和判断恶性程度及预后有重要参考价值。

Abstract: Objective To investigate the evaluation of combined determination of serum CA153 and TSGF in diagnosis of gliomas. Methods Immune radiation measure analysis and Spectro-photometric method were used to detect the serum level of CA153 and TSGF in 58 patients having gliomas. Results The serum level of CA153 and TSGF of the gliomas group was significant higher than that of the The benign tumor group and healthy group (P<0.05). The serum level of CA153 and TSGF in gliomas with different degrees of malignant was significantly different(P<0.05). Diagnostic efficiency of combined determination of serum CA153 and TSGF were higher than those of the single index in diagnosis of gliomas. Conclusion Combined determination of CA153 and TSGF plays an important role in early diagnosis pathologic stage and prognosis of gliomas.

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