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肛管直肠恶性黑色素瘤29例临床分析[J]. 肿瘤防治研究, 2000, 27(04): 294-295. DOI: 10.3971/j.issn.1000-8578.1310
引用本文: 肛管直肠恶性黑色素瘤29例临床分析[J]. 肿瘤防治研究, 2000, 27(04): 294-295. DOI: 10.3971/j.issn.1000-8578.1310
The Clinic Analysis in 29 Cases of Anorectal Malignant Melanoma Tumor[J]. Cancer Research on Prevention and Treatment, 2000, 27(04): 294-295. DOI: 10.3971/j.issn.1000-8578.1310
Citation: The Clinic Analysis in 29 Cases of Anorectal Malignant Melanoma Tumor[J]. Cancer Research on Prevention and Treatment, 2000, 27(04): 294-295. DOI: 10.3971/j.issn.1000-8578.1310

肛管直肠恶性黑色素瘤29例临床分析

The Clinic Analysis in 29 Cases of Anorectal Malignant Melanoma Tumor

  • 摘要: 目的 通过肛管直肠恶性黑色素瘤29例临床分析,研究各种因素对生存期的影响。方法 通过29例肛管直肠恶性黑色素瘤的5年追踪,临床分析,比较年龄、性别、肿物浸润肠腔的范围,肿瘤大小,区域淋巴结有无转移及各种治疗方法对生存期的影响,探讨提高生存率、延长生存期的治疗手段。结果 肛管直肠恶性黑色素瘤无特殊的临床表现,极易误诊为直肠癌、直肠息肉和血栓性痣。诊断必须依据组织病理学。如能早期诊断,且行以经会阴直肠根治术为主,辅助化疗、免疫治疗,就能延长生存期,提高生存率。单纯化疗、放疗效果不理想。结论 加强对肛管直肠恶性黑色素瘤的认识,早期确诊,行Miles氏手术为主的综合治疗是延长此病生存期,提高生存率行之有效的方法。

     

    Abstract: Objective To study all kinds of factors' effect on survived period by the clinic analysis in 29 cases of anorectal malignant melanoma tumor. Methods With the follow-up of five years' clinical observation, the age,the sex,the scope which the mass infiltrated to the rectal axis,the size,regional lymph node transference and effect of treatment methods on survived period,were compared in order to find out more effective treatment mothods to prolong the survived time. Results Anorectal malignant melanoma has no special clinical manifestation,so it is easy to be confused with rectal carcinoma,rectal polyp and thrombtic.It must be diagnosed by pathology.Given early diagnosis,Miles operation and regional lymph node cleaning and chemotherapy,immunotherapy after operation,the patients can prolong the survival time.It is not ideal with single chemotherapy and radio therapy. Conclusion It is the effective ways to prolong the survival time by strenghtening the knowledge,definite diagnosis,synthetical treatment which mainly rely on the miles operation and immunotherapy,chemotherapy after operation.

     

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