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子宫内膜癌放射治疗疗效分析

Analysis of radiotherapy of effect for enclometrial carcinoma

  • 摘要: 为了观察放疗对子宫内膜癌的影响。对我院1987年~1990年72例接受放疗的子宫内膜癌患者进行分析。根据1971年FIGO标准,Ⅰ期24例、Ⅱ期41例、Ⅲ期7例。病理分类:腺癌58例、腺鳞癌6例、透明细胞癌2例。年龄:35~76岁,平均年龄57.96岁。治疗方法:全盆大野照射,盆腔中平面剂量为DT40GY~50GY,腔内治疗X点剂量20~40GY,A点剂量20GY~30GY。5例单纯体外照射、14例单纯腔内、53例体外加腔内。38例患者放疗后行全子宫及双侧附件切除,术后病理证实,部分病例无肿瘤残存。腔内放疗作为全盆外照后的补充放疗能有效地控制子宫内膜肿瘤。总五年存活率为52.6%,Ⅰ~Ⅱ期五年存活率为:Ⅰ期58%、Ⅱ期51.14%、Ⅲ期28.77%。单纯放疗可适用于Ⅰ、Ⅱ期子宫内膜癌不宜手术的患者。对病期较晚、手术不能切除干净的晚期患可行全量放疗,然后争取行子宫及双侧附件切除。为了提高单纯放疗疗效,在放射治疗前临床医生应尽可能全面的掌握肿瘤的信息。

     

    Abstract: To observe the effect radiotherapy in treating the patients with endomtrial carcinoma, this article contains 72 patients who received radiotherapy in our hospital from 1987 t0 1990. According to FIGO staging 1971, there were 24 cases in stageⅠ,41 cases in stage Ⅱ,7cases in stageⅢ. The median age was 57. 96 years. The whole pelvis radiation alone 5 cases, afterloading irradiation 14 cases,external irradiation supplemented by intracavitary radiation 53 cases, 38 cases were treaed by radiotherapy followed by surgery. Postoperative pathologic peimens proved that the cancer is not found in some specimens, radiotherapy is important to endometrial careinoma. The overall 5-year survival rate was 52.67%; 5-year survival rates of Ⅰ~Ⅲ stage were 58%,51. 14%and 28.77%.The results suggested that exernal irradiation supplemented by intracavitary radiation provide the best therapentic effect.To improve effectiveness of radiotherapy for endomtrial carcinoma and design the plan of radiotherapy, doctors should get more details of cancer by C. T, Ultrasound and MRI.

     

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