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我国营养干预和中草药阻断食管癌变的Meta分析

陈志峰

陈志峰. 我国营养干预和中草药阻断食管癌变的Meta分析[J]. 肿瘤防治研究, 1998, 25(6): 466-469.
引用本文: 陈志峰. 我国营养干预和中草药阻断食管癌变的Meta分析[J]. 肿瘤防治研究, 1998, 25(6): 466-469.
Chen Zhifeng. he Meta-Analysis For Both Nutrition Interference And Chinese Herbal Mallcine's Interruption's Usefulness in prevention of Esophageal Cancer in china[J]. Cancer Research on Prevention and Treatment, 1998, 25(6): 466-469.
Citation: Chen Zhifeng. he Meta-Analysis For Both Nutrition Interference And Chinese Herbal Mallcine's Interruption's Usefulness in prevention of Esophageal Cancer in china[J]. Cancer Research on Prevention and Treatment, 1998, 25(6): 466-469.

我国营养干预和中草药阻断食管癌变的Meta分析

he Meta-Analysis For Both Nutrition Interference And Chinese Herbal Mallcine's Interruption's Usefulness in prevention of Esophageal Cancer in china

  • 摘要: 本文应用Meta分析方法,对我国近10年营养干预和中草药阻断治疗降低食管癌高发区癌变率的13篇研究文献进行统计合并,其中食管上皮细胞重度增生(重增)治疗组累积病例为4574例,对照组3946例;食管上皮细胞轻度增生(轻增)治疗组累积病例为2634例,对照组2534例。以对照组与治疗组的癌变率差值d作为效应值。结果重增人群营养干预后d=0.0063,95%CI(-0.2459~0.2585),轻增人群d=0.0053,95%CI(-0.0018-0.0124);而重增人群中草药阻断治疗后d=0.0613,95%CI(0.0456~0.0769)。资料的齐性检验均无显著性差异(P>0.05)。本文Meta分析表明我国营养干预手段对降低食管癌高危人群和普通人群的保护作用尚不肯定,而中草药对降低高危人群癌变率疗效值得重视。

     

    Abstract: Using the method of Meta-analysis, tow writers make a stahshcal analysis to lhirteen study-references of recent 10 years that major in both nutrihonal inteifemee and Chinese herbal medicine's interruption's heatment having been used to reduce the incident rate of esophageal cancer in the high-risk area in China. The ccumulative cases of the heated group of serious epithelial hmplasia of esophageal are 4574 cases, and the control group are 3946 cases; the cumulative cases of the treated group of slight epithelial hyperplasia of esophageal are 2634 cases and the control group are 2534cases. The difference in rate d of both the control group and the treated group's incident of the cancer in used as the figure of effect. After nutrtion-interferring, the patients of serious epithelial hyperplasia of esophageal d = 0. 063, 95% CI (-0. 2459 ~ 0. 2585); the Patients of slight epithelial hyperplasia of esophageal d = 0. 0053, 95% CI(-0.0018 ~ 0. 0124); and after treating with chinese herbal medicine in the group of serious epithelial hypeofasia of esophageal d = 0. 0613, 95 % CI(0.0456 0.0769). There are no signifificant difference in all the date for test consistency. Meta-analysis of this Passage indicates that use by means of nutrihonal interference toreduce the high-risk group of esophageal cancer and to protect the common group is not really sure. But chinese helbal medicine's effects in treating esophageal precancerous pathological changes are worthy of being highly considered.

     

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出版历程
  • 刊出日期:  1998-12-04

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