Abstract: 42 patients with breast cancer who had already undergons mastectomv reccived whole bone scanning and X-ray films. Follow-up was available for all 42 cases ran ging from 6 to 24 months. Among 21 patients with no pain 14 cases were positive in whole bone scanning; 7 negative. Among them 2 cases were confirmed skeletal metastases during followup. Among 21 patients with pain 16 cases were positive in whole hone scanning, 5 egative. Among them 9 cases were confirmed skeletal metastases during follow-up. The above results showed that positive accuracy rate of bone scanning was 36.6 per cent(11/30) without false positive. And positive accuracy rate of X-ray bone film was 77.3％ (7/9) with false positive (2 cases) and false negative (4 cases) In summary radionuclide bone scanning is a method of finding and diagnosing metastatic bone lessions for postoperative patients with breast cancer. In combination with X-ray examination, it has higher diagnostic reference value but its considerable false positive rate (63.4％) should be analysed further