二苯并(a、h)蒽诱发小鼠肺腺癌超微结构的研究
UITRASTRUCTURAL STUDY OF MICE PULMONARY ADENOCARCINOMA INDUCED BY DIBENZ (A, H) ANTHRACENE
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摘要: 用二苯并蒽诱发了高发病率(90%以上)小鼠肺肿瘤,其中80%以上为腺癌。电镜观察发现有的腺癌具有肺泡Ⅱ型上皮细胞的特点,有的具有Clara细胞的特点,多数腺癌则兼具有Ⅱ型上皮细胞及clara细胞的特点。Abstract: The high incidence of lung cancer in mice induceb by dibenz (a, h) anthracene is reported, reaching to more than 90%, among them 80% tumors were adenocarcinomas. Electron microscopy revealed that some adenocarcinomas possessed features, of alvelar Type I cell, some possessed Clara cell features, and someother adcin eeareinomas possessed common features of the both.