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脂质体包封甲氨喋呤对大肠癌细胞系的体外生长抑制作用

THE INHIBITORY EFFECT OF LIPOSO"NE.-ENCAPSULAT METHOTREXATE (MTX) ON IN VITRO GROWTH OF LRGE BOWEL CANCER CELL LINE

  • 摘要: 利用3H-TdR掺入技术同时观察了不同浓度的MTX脂质体对大肠癌细胞系HR8348体外生长的影响。实验结果表明,MTX经脂质体包封后,其抑制肿瘤生长的作用比相同浓度的游离MTX明显增强。

     

    Abstract: The effect of liposome-encapsulated MTX on in vitro gro wth of large bowel cancer cell line HR-8348 was assessed by incorporation of tritiated thymidine (sH_TdR) into tumor cells.

     

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