伴多量上皮样组织细胞的T细胞淋巴瘤(Lennert淋巴瘤)二例报告

MALIGNANT LYMPHOMA WITH A HIGH CONTENT OF EPITHELIOID HISTIOCYTES, MORFHOLOGICAL., HISTOCHEMICAL. AND IMMUNOLOGIGA L OBSERVA TIONS OF TWO CASES

摘要: Lennert淋巴瘤是近十余年来始见于文献的一种非何杰金氏淋巴瘤。据不完全统计,国外报道已逾百例,国内也发现了30余例,但多系在回顾性调查中单纯依据形态学标准进行诊断的。经功能性诊断者,国内外累计亦不超过30例,而国内只有5例。我们于1984年上半年连续遇到两例,对其组织学、免疫学、组织化学等方面的观察,证实为T细胞来源。

Abstract: The results of multlparanigter. studies of two cases of malgnant lymphoma with a high content of epithelioid histiPcytes (so-called Lennert's, lymphoma) are presented, The patients were loth male and middle-aged;They had gener;zed lymphadenopathy but no other clinical symptoms, Microscopically, both cases showed diffuse prolifer- ation of atypical lymphoid cells and small clusters of epithelioid histiocytes sacttered throughout theneoplastic cells,AcP,ANAE staining patterns were globular for lymphoid cells and diffuse for histiocytes, In:munoperoaidase methods for intracy- toplasmic immunoglobulins, were negative, Then tumor cells in suspensions formed spo- ntaneous rosettes with sheep erythrocytes, The, findings further support a T cell origin for Lennert's lymphoma as previously .reported in literature,

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