Abstract: 317 patients of malignancies were treated by"An Liu Ru" (ALR) (5-fluorouracil composite emulsion) in 26 hospitals. ALR was given intravenously with a daily dose of 10～50ml,the range of total dose was 400～2450ml; or orally with a daily dose of 30～60ml, the range of total dose was 600～7320ml, The response rates(PR+MR) OF ALR were 23%，21%，8% and 7% respectively on cancer of bowel,stomach. esophageal and cardia. The object response rates were 31%,30%,12% and 11% respectively for those cancer just mentioned above.The symptomatic and objective response rates were62%,58%,42% and 24% respectively.The side effects were anorexia,nausea,vomiting and phlebitis in a few patients The effect of ALR on alimentary tract cancer was better,and the side effect was small.