结节硬化型何杰金氏病的再分级及其临床意义

SUBCLASSIFICATION AND ITS SIGNIFICATION OF NODULAR SCLEROSIS IN HODGKIN'S DISEASE

摘要: 结节硬化型(NS)何杰金氏病(HD)在何杰金氏病的四型分类中是相对独立的亚型。本文报告10例NS病例,并根据Bennett的标准再分成NSⅠ级及NSⅡ级。探讨此种分级的临床意义。本文认为年龄,性别与预后无明显关系。临床分期与预后有一定的关系。一般说,早期病例预后较好,晚期病例预后较差。纵隔受累的病人预后较差。多种方法治疗的病人预后较单一方法治疗要好。组织学再分级与预后的关系更明显,NSⅠ此NSⅡ级病人的预后好。如果将组织学分级再结合其它因素综合分析,就能更好地制定治疗方案及估计预后。

Abstract: Ten cases nodular sclerosis(NS) type of Hodgkin's disegse were distinguished two grades (NSI and NSII) according the criteria of British National Lymphoma Investigati0n(BNLI) . NSI was eight: cases, NSII two cases. The subcIassification of NS in Grade 1 and 2 is a progn ostic factor in survival independent of other factor.