恶性淋巴肉瘤患者尿中多胺含量的分析研究

ASSAY OF URINARY POLYAMINES IN PATIENTS WITH LYMPHOSACOMA

摘要: 本文报道32例恶性淋巴肉瘤患者尿多胺的含量分析结果,尿多胺含量比正常人明显增高,比正常均值增高的倍数各为:腐胺1.52倍,精脒0.58倍,精胺4.52倍。本组患者一项尿多胺增高者占总例的100%,两项多胺增高者占81.25%,另外,在滤纸电泳图谱的腐胺和精眯色带之间又发现一分离清晰的新色带,在本组患者尿中亦见增多,为正常均值的1.55倍,增高的出现率为37.5%。表明尿多胺含量分析可作为恶性淋巴肉瘤患者辅助诊断的参考。

Abstract: The amounts of urinary polyamines of 32 patients with lymphosacoma were determined. The urinary polyamines in these patients were significantly higher than those in normal subjects. The putrescine, spermidine and spermine had respectively increases by 1.52 times, 0.58 times and 4.52 times as compared with those in normal subjects.Of the patients, 100% had a rise in one of the three polyamines, while 81.25% in two. Between the putrescine and spermidine in the electrophoregram a histamines'like substance was detected. Whose value was also high, and 1.55 times higher than the normal value, with a positive elevated rate of 37.5%, The assay of urinary polyamines can be used as an auxiliary method in the diagnosis of lymphosacoma.