Abstract: Fifty-eight patients with liposarcoma survived more than five years were discussed in this paper. We concluded, females patients who had a long clinical course, smaller mass, well differentiated and focus occurred at head and neck or lower extremities, the prognosis of combined and rabiotherapy was good, hut patients in middle age, tumor site occured at trunk and upper extremities, multicentric, and metastasis, the prognosis was poor.