Abstract: From May treated by 1988 to August 1988, thirty-seven patients a-interferon (IFN) and. radiother with mailgnant tumor.The fe'sults suggested,of patients with evaluable tumor, the propor.tin.n apy, rate complete and partial responses patients was 95,2，remission consitie.n forsomeasbetterthanweezpeeted.seen malignant patientsin the growing of metastatic tumor that treated by IFN, the fever,weariness and weak etc,.major complications of TFN were.