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肺腺癌胸水刺激肿瘤细胞生长的研究

STUDIES OF THE TUMO0R CELL GROWTH STIMULATED BY MALIGNANT LUNG ADENOCARCINOMA PLEURAL EFFUSION

  • 摘要: 本文研究了人肺腺癌恶性胸水对体外培养的肿瘤细胞系(人鼻咽癌细胞系CNE)生长的影响。通过显微镜观察,制作生长曲线以及使用放射性同位素~3H标记的胸腺嘧啶渗入DNA合成实验,我们首次发现了恶性胸水对体外培养的肿瘤细胞系CNE具有生长刺激作用。其中2%浓度的该胸水具有与10%浓度小牛血清相当的刺激作用。

     

    Abstract: We use a human nasopharynx epithelial cell line CNE as an indicator to the effects of pleural effusion from andTdRa lung adenocarsinoma pat'ent on tumor study.cell growth.Growth curve incorporation reveal that this pleural effusion can stimulate CNE cell growth in vitro,It can enhance the growth actioff=of calf, serum.' Different stimulating tions of pleural effusion.We suppose that action is observed various this growth stimulating action stimulating concentra-is certainfactors type of growth stimulating factors in pleural effusion. Occurrencedue to of these in pleural effusion may be related to tumor growth in mV0

     

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