肿瘤相关抗原在肠化上皮中表达的免疫组化研究

AN IMMUNOHISTOCHEMICAL STUDY ON THE EXPRESSION OF TUMOR ASSOCIATION ANTIGEN IN THE INTESTINAL METAPLASIA OF GASTRIC MUCOSA

摘要: 本文应用抗大肠型粘液单抗LIMA及抗胃癌单抗MG₇并ABC法对胃粘膜肠上皮化生进行了对照观察,结果提示LIMA在胃良恶性疾病所伴的肠化上皮中均有不同程度的阳性率;而MG₇阳性率低,但在胃癌癌组织中阳性率达96.2％,具有较高的选择性。作者认为LIMA用于大面积的肠化普查,作为一监测指标,从中筛选出高危病例,对其阳性病例随访时再并以MG₇染色可以证实胃癌的存在。

Abstract: Digestive Laboratory. Xijing Hospital, Fourth Military Medical University, Xi'an Anti-LIMA antibody may be used in the mass screening among those with intestinal metaplasia and that in the close follow-up of the positive cases. MGs may be serve to select the early gastric cancer.