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甲状腺肿瘤核仁组成区的定量研究

A QUANTITATITIVE STUDY OF NUCLEOLAR ORGANIZER REGIONS IN THYROID TUMORS

  • 摘要: 本文采用银染核仁组成区(AgNOR)技术,对甲状腺良恶性肿瘤组织中核仁组成区(NOR)进行了研究。结果表明:甲状腺良恶性肿瘤之间,低度恶性和高度恶性之间,良性肿瘤和癌前病变之间以及恶性肿瘤和癌前病变之间NOR的计数均有显著差异,NOR大小和分布也有不同。本研究提示:NOR计数在鉴别良恶性病变,判断肿瘤生物学行为方面有重要意义;AgNOR技术在肿瘤病理研究中是一种极有希望普及应用的新方法。

     

    Abstract: A study of nttelealar organizer regions (NOR) inmalignant and benign tumors was performed-with-the method of Ag-staining nucleolar organnizer regions (AgNOR). Results shew that the differences of the numbers of NOR, benigh tumors were compared with slight malignant ones, severe malignant tumors were compared with slight malignant ones, benign tumors and malignant ones were compared with Precancerosis, were significant. The sige and distribution of NOR was different, this. article suggest that NOR counting is very important for differetiating benign tumors from malignant ones, and eveluating biological characters of tumors. Ag-NOR is hepfal new method which may be extensively used in the pathological studies of tumors.

     

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