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111例胃癌CEA的免疫组化与预后关系

陈莉, 毛毓斌

陈莉, 毛毓斌. 111例胃癌CEA的免疫组化与预后关系[J]. 肿瘤防治研究, 1991, 18(2): 95-98.
引用本文: 陈莉, 毛毓斌. 111例胃癌CEA的免疫组化与预后关系[J]. 肿瘤防治研究, 1991, 18(2): 95-98.
THE RELATIONShIIP BETWEEN PROGNOSIS AND IMMUNO-HISTOCHEMISTRY OF CEA IN GASTRIC CAREINOMA:111 CASES[J]. Cancer Research on Prevention and Treatment, 1991, 18(2): 95-98.
Citation: THE RELATIONShIIP BETWEEN PROGNOSIS AND IMMUNO-HISTOCHEMISTRY OF CEA IN GASTRIC CAREINOMA:111 CASES[J]. Cancer Research on Prevention and Treatment, 1991, 18(2): 95-98.

111例胃癌CEA的免疫组化与预后关系

详细信息
    作者简介:

    陈莉: Chen Li

    毛毓斌: et al

THE RELATIONShIIP BETWEEN PROGNOSIS AND IMMUNO-HISTOCHEMISTRY OF CEA IN GASTRIC CAREINOMA:111 CASES

  • 摘要: 本文对111例胃切除标本的组织采用ABC免疫酶标技术进行癌胚抗原的反应观察及其预后关系的研究。结果表明:乳头状腺癌,管状腺癌,粘液癌主要为CEA(+),低分化癌、未分化癌与印戒细胞癌为CEA(++)。乳头状腺癌,管状腺癌以CEAⅡ型分布为主,其它类型以Ⅰ型分布为主。肿瘤组织中CEA的含量与肿瘤的淋巴结转移呈正比。在CEA反应不同的三组中,五年存活率有显著的差异。无淋巴结转移时,以CEA(-)组存活率最高;有淋巴结转移时,以CEA(+)组存活率最高;各组均以CEA(++)组存活率最低。

     

    Abstract: Gastric cancer specimens obtained fro m 111 patients who had undergone surgery were stained for carcinoembryonic antigen (CEA) by the avidinbiotin-perogidase complex (ABC) method. These findings suggest that CEA rectivity can be used as a diagnostic and prognostic marger for gastric carcinoma. The petients without lymph node metastasis 5-year survival rate was high especially in the CEA(-)group (81.82%), the survival rate of the CEA(+) group and the CEA(++) group were 53-97% and 10.95%. The patients with lymph node metastasis 5-year survival rate was low in the CEA(++) group. The survival rate of the CEA(++) group CEA(-) and CEA(++) group was 60%, 20.2% and 4.5%, respectively.

     

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出版历程
  • 刊出日期:  1991-06-04

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