Causes of neck radiation fibrosis in patients with NPC-An analysis of 87 cases
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摘要: 本文分析了87例鼻咽癌患者放疗后1~15年,有40例出现不同程度颈部纤维化改变,占46%.其中轻度26例(29.9%),中度12例(13.8%)重度2例(2.3%).应用C0(60)γ线及8MvX线纤维化发生率分别为35.1%,41.6%,而应用γ线+120~140byX线,γ线+10~14Mevβ束均为83.3%,放射剂量是影响纤维化的最重要因素之一,<800MG,,70例中27例出现纤维化,占38.6%,≥8000CGy,17例中13例出现纤维化,占76.5%(P<0.01).对颈部淋巴结给一定剂量后估计难以消失的,不应盲目加量.Abstract: NPC patients 1 - 15 years after their radiotherapy which led to nab fibrosis in 40 patientswere analysed. When 60C0-γray or 8Mv X-ray was delivered, the incidence of fibrosis was only35. 1 %, 41. 6 %, respeCtively, while γ-ray combined with 120～ 140Kv X -ray or 10-14Mev β raygiven, the incidence rose to 83. 3%. The results shewed the most important cause of fibrosis was thetumor dose. When it was800cGY, only 27 of 70 patients (38. 6%) developed fibrosis, when≥8000cGY, 13 of 17 causes (76. 5 % ) mauifersed neck fibrosis, (P0. 01 ). Futher radioation shouldnot be given blindly after fairly high dose to neck nodes which were dsthated not to be eliminatedby radiotheray.
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Key words:
- NPC /
- Radiotberay /
- Fibrosis
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