Abstract: It is reported that 28 patients with moderate or advanced ovarian carcinoma were treated with abdominal chemotherapy and intravenous chemotherapy. This method is better for eliminenting the residual carcinoma and prolonging survival time. Abdominal chemotherapy was first succesed by a single puncture. 50-150ml liquid containing 40-80mg DDp was injected into the abdominal cavity and no complications appeared. It was confirmed that residual carcinomas were reduced or extinguished by B-us or second-laparotomy. This therapy is better to primary ovarian carcinoma than metastatis carcinoma.