食管癌放疗剂量的临床探讨

A clinic approach in the dose of radiotherapy for esophageal carcinoma

摘要: 1990年6月至8月采用随机分组方法对90例食管癌患者进行⁶⁰Co体外照射,45例行大剂量分次照射,45例行常规剂量分次照射。全部病例随访至1992年9月,结果:大剂量分次照射组的1年和2年生存率明显高于常规剂量分次照射组,分别达89%和44%。并分析了两组放疗失败的主要原因为局部未控或复发,而大剂量分次照射组显然低于常规剂量分次放疗组。因此,我们推荐食管癌的放疗宜采用大剂量分次照射。

Abstract: A series of 90 esophageal carcinoma patients.They were irradiated by randomomized methord.45 cases were received large dosage(60 Gy/5wk) fraction irradiation and other received rular dosage(70Gy/7wk) fraction erradiation.All patients had been followed up in september,1992.The result indicated that the survival rate of and 2 year in large dosage group was much better than in rular dosage group.The main cause of failure was local uncontrol and recover and it was lower in the large dosage group than in the another.We suggested the radiation of Esophageal carcioma had better take large dose fraction irradiation.