血清中GST和B－GST的测定对恶性肿瘤的诊断意义

Diagnostic value to determination of serum GST and B-GST for the patients with malignant tumor

摘要: 本文用Adachi Y法和Shivendra V法分别测定了正常人及肿瘤患者血清中谷胱甘肽硫转移酶(GST)及其同工酶碱性谷胱甘肽硫转移酶(B-GST)的活性。结果表明:血清中B-GST活性值在肝癌时较正常明显升高(p<0.05),阳性率为55.6%。血清中GST活性在肝癌、肺癌、乳腺癌、宫颈癌、鼻咽癌及食道癌时与正常人无显著差异(p>0.05)。

Abstract: The activities of glutathione S-transferase(GST) and basic glutatione S-tranferase(B-GST) in serum for healthy adults and patients with tumor were assayed with Adachi method and Shivndra method respectively.In results,serum B-GST activities significantly incresed only in cases of hepatoma(P<0.05),the positive rates in 55.6%,serum GST activities in cases of hepathoma,lung cancer,breast cancer,cancer of uterine cervix,nasopharyngeal cancer and cancer of esophagus were not different significantly as compared to healty adults(P>0.05).