肺癌患者血清Mn-SOD和LSA对比观察

Comparative observation of Mn-SOD and LSA in patients with lung cancer

摘要: 同时检测了68例肺癌、28例肺良性疾病、35例健康成人血清锰超氧化物歧化酶(Mn-SOD)活力和脂质结合唾液酸(LSA)含量,Mn-SOD的阳性率为77.94%,诊断正确率为79.17%,LSA的阳性率为70.6%,诊断正确率为82.8%,二者相似;Mn-SOD和LSA对各型肺癌均有较高的检出率;15例肺癌患者Mn-SOD及LSA水平变化与手术切除疗效相关。结果提示,Mn-SOD及LSA在肺癌的诊断、鉴别诊断及疗效监测方面有较大的临床意义;Mn-SOD与LSA联合检测优于单项检测。

Abstract: Mn-SOD activity and LSA level were measured in 68 patients with lung cancer,28 patients with benign pulmonary disease and 35 normal subjects.The results showed that the positive rate(77.94%) and diagnostic accuracy rate(79.17%) of Mn-SOD activity for lung cancer were equal to those of LSA.The positive rate and diagnostic accuracy rate of LSA level for lung cancer were 70.6% and 82.8%.Mn-SOD activity,LSA level and their positive rate related to the types of lung cancer.The changes of Mn-SOD activty and LSA level in 15 patients with lung cancer were related to the results of surgical treatment.