大肠腺癌AgNOR计数的预后意义

PROGNOSTIC SIGNIFICANCE OF AgNOR COUNTS IN ADENOCARCINOMA OF LARGE INTESTIN

摘要: 本文对44例大肠腺癌进行AgNOR计数研究,结果显示生存期在5年以上的病例AgNOR计数(4.03±1.66)明显低于生存期不足5年的病例(6.19±2.18),两者差异具有高度显著性(P<0.005).与肿瘤的组织学分级、大体类型、生长方式及浸润深度等病理因素比较,AgNOR检测在判断肿瘤预后方面具有重要意义,可作为判断肿瘤预后的一种指标.

Abstract: This paper analyses AgNOR Counts in 44 cases of adenocarcinoma of large intestin. The meannumber of nucleolar organizer regions pernecleus of patients with survived for more than 5 yearsare strikingly lower than those patients with survived for less than 5 years (P0. 005) AgNORCounts are the chief determinant of prognosis, and it is an important prognostic indicator for patients carcinoma.