双途径介入治疗晚期肺癌
Two Route Interventional Chemotherapy in the Treatment of Later Lung Cancer
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摘要: 我们自1990年至1993年, 对87例晚期肺癌患者采用支气管动脉及肺动脉双途径介入化疗, 收到满意疗效。 术后平均生存18个月。 与此同期单纯支气管动脉介入200例, 术后平均生存10.5个月, 经过双途径介入化疗大部分病人临床症状缓解, 提高了生活质量, 部分病人重新获得了手术机会, 生存期较单纯支气管动脉介入明显延长。 表明肺动脉与支气管动脉同时介入, 较单纯支气管动脉介入化疗疗效好, 可以互相弥补其不足, 更广泛地杀死癌细胞。 是一种有效的姑息治疗手段。Abstract: cases of later lung cancer were treated by Two Route arterial Chemotherapy (TRAC) viabronchial artery and pulmonary artery. They were all stage Ⅲ-Ⅳ cases (TNM stages) in thisgroup. Selective bronchial arteriography showed the tumer's nourishing blood vessels. TRIC wasperformed injection the bronchial artery with CBP 300mg, ADM 30mg and VP-16 300mg; followed injection the pulmonary artery with VCR ling and MMC 4mg, 5-Fu 500mg etc for ten days. Goood results were achieved CR 90.87% of cases; PR 55.17%; MR 35.63%; NC 5.7%, PD 3.4%. TRAC was an effective palliative treatment way in later lung cancer.
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[1] 袁建华. 401例支气管肺癌供血动脉分析. 影像诊断与介入放射学, 1994, 2. [2] 腾皋军. 支气管肺癌的双重供血. 中华放射医学杂志《 1991, 23. [3] 尹玉承. 选择性药物连续灌注治疗头颈部恶性肿瘤. 实用肿瘤学杂志, 1994, 2. [4] 华新民. 晚期肺癌的综合治疗进展. 实用肿瘤, 1992, 4. [5] 任安综. 选择性支气管动脉灌注化疗药物治疗原发性肺癌. 国外医学呼吸分册. 1991, 3
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