肺癌化疗中胸腺肽(Thymopeptides)治疗的作用评价

The eveluatin of thymopeptides on chemotherapy of lung cancer

摘要: 168例晚期肺癌患者, 分对照和处理二组, 对照组单用化疗, 处理组在化疗同时合并使用胸腺肽。治疗前后均测定外周血T淋巴细胞亚群(CD₃、CD₄、CD₈以及T₄/T₈比)和IgG、Iga、IgM。同时评判生活质量(kps)及观察胸片上癌灶变化。结果表明, 胸腺肽对提高患者细胞免疫功能有显著意义, 但对癌灶的缩小无明显作用。
- 肺癌 /
- 化疗 /
- T淋巴细胞亚群 /
- 胸腺肽
Abstract: One hundred sixty eight patients suffered with late Lung Cancer were devided into two groups. In one group(control group), pationts trexted only with chemotherapy, and the another, thymopeptides were combined with chomothyerapy. The Subdivision groups of T Lymphocyted:CD₃、CD₁、CD₅ and T₁/T₈ rates, within the peripher-al blood and immunity glubulins of IgG、IgA、IgM were detected before and after therapy, Living qualities(KPS) and changes of cancer Lesion by chest finlms of patients were alao evaluated, as well. The Canclusion derived from these invastigations have shown, theymopeptides will promote sig-nificantly the immunity capacities of the patients, but seems not affectires on inproremont for Lung cancer Lesion.
- Lung cancer /
- chemotherapy /
- Subdirision of T Lymphocytes /
- Thymopeptides

[1]	马宝郦, 肖祥熊. 医学免疫学. 第一版. 上海:同济大学出版社, 1987.179
[2]	葛依工, 等. 移植性肝癌大鼠外周血和脾脏T细胞亚群变化的动态观察。中华肿瘤杂志, 1988,10(6):417.
[3]	林飞卿, 等. 医学基础免疫学. 第一版. 上海:上海医科大学出版社, 1992,331.