女性肺癌的临床特点
Carcinoma of the lung in women
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摘要: 本文报道我院1978年1月~1992年7月间经外科治疗、病理证实的女性肺癌210例,占同期收治肺癌的20.8%,男女比例为3.8:1.女性肺癌有其明显的临床特点:1.发病年龄低于男性,年龄越小女性肺癌比例越大,<30岁者女性占43.5%(10/23);2.肺癌的组织类型中,女性腺癌发生率最高达44.8%,鳞癌占22.4%,与男性肺癌相比较其腺癌、类癌及其他低恶性肿瘤发生率较高(P<0.01),无大细胞癌;3.女性肺癌切除率为77.1%,低于男性,手术死亡率4.3%,高于男性;4.切除术后1、3、5年生存率为74.1%,39.3%及34.4%,均高于男性.预后较好可能与女性腺癌细胞浆中雌激素激体有关,其性别可作为估计预后的一个因素.Abstract: This article reported 210 cases of carcinoma of the lung in women which was undergone surgical treatment and identified pathologically during 1, 1978 to 7, 1992. This was 20. 8% of the patients with lung cancer addmitted in the same period. The male to female incidence of lung cancer is 3. 8 ;1. Obvious clinical features was shown in women with lung cancer. 1. The age of carcinoma of the lung in women was younger than the age of men. The younger the patients with lung cancer, the more incidence the carcinoma of the lung in women. The incidence of the lung cancer in women was 43. 5% (10/23) of all patients with lung cancer in 30 years old or younger. 2. Adeoocarcinoma had higher incidence reaching to 44. 8% in women, then squamous carcinoma 22. 4%. In women the incidence of adenocarcinoma, carcinoid and other lower malignant tumor was higher, but there was none of the large cell carcinoma. 3. The resectable rate of the lung cancer in women was 77. 1 %, lower than in men, but pcotoperative mortality was 4. 3 %, higher than in men. 4. The 1-, 3-, 5-year's survival rate was respectively 74. 1 %, 39. 3%, 34. 4%. All of .them was higher than in men. The good prognosis was rebated to the recepator of estrogen in the adenocarcinoma cell. The data showed that sex may be an important factor suggesting prognosis.