Abstract: Abstract The incidence rate of juvenile primary hepatic cancer has gone up these years.This article reports the clinical observation of 53 cases of juvenile primary hepatic cancer.We compared the juvenile group with the adult group item by item. Our findings demonstrated that the juvenile primary hepatic cancer had many distinguishing features.The juvenile attacked this disease very quilkly and the course isvery short. The rate of misdiaglose in juvenile is high while cure rate low.All the 53 cases of juvenile patients had the symptom of hepatomegaly(100% ).The rate of positive AFP is (84%).The juvenile hardly had the symptom of cirrhosis.The treatment of juvenile primary hepatic cancer is Very difficult and the mortality is absolutly high. So we should pay more attention to the juvenile primary hepatic cancer.