Abstract: This paper reported that the Swiss Mice with Ehrlich Solid Carcinoma were treated by single hyperthermia and the hyperthermia combined with mitomycin C.The result indicated that the cure rate of single hyperthermia was 50% and the cure rate of hyperthermia combined with mitomycin C was 88%.It is suggest the latter treatment may raise the effect of hyperthermia for tumors.The study shows the mitomycin C can also prevent the emergence of heat resistant in addition, the DNA synthesis in tumors may be damaged by pertbermiaorm mitomycin C.They have the cooperative actionin treatment of tumor.